“Contrary to some previous findings, we now know that vascular damage caused by premature inflammation, such as higher arterial stiffness in adolescents, can lead to high blood pressure, hypertension, insulin resistance, obesity and increased heart rate,” said Andrew Agbaje, from the University of Eastern Finland. physician and clinical epidemiologist.

The current study was conducted among 3,862 adolescents aged 17 years and followed for 7 years to 24 years. The results showed that nearly 1 in 3 men and 1 in 2 women are at higher and worsening risk of inflammation by age 24. The researchers found that increased inflammation in men may lead to higher carotid wall thickness, a sign of preclinical atherosclerosis.

Vascular Consequences of Inflammation

On the other hand, increased inflammation in women may lead to higher arterial stiffness. According to the researchers, these gender-specific negative effects of inflammation on various aspects of blood vessels are a novel finding that may help to understand the pathogenesis of early-onset cardiovascular disease, as well as the optimal approach to treatment. Surprisingly, the researchers observed that being overweight or obese did not adversely affect the premature vascular damage of inflammation.


“For example, foods rich in fruits, vegetables, and fiber have important anti-inflammatory properties and should be encouraged in the family. However, foods rich in saturated and trans fats, salty and fried foods, red and processed meats, as well as sugary drinks, pastries, and sweets can cause premature atherosclerosis. can be associated with injury because they can significantly increase inflammation,” says Agbaje.

“These new findings should strengthen our approach to preventing premature vascular damage in adolescents. Public health professionals, pediatricians, and health policy makers should encourage families to make healthier dietary choices. One approach is to significantly lower the prices of fruits and vegetables through government subsidies and tax returns, ” says Agbaje.

Source: Eurekalert

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